Carboxylic Acids Esters, Amines and Amides

Carboxylic Acids Esters, Amines and Amides

Carboxylic Acids Esters, Amines and Amides Amines Reactions of Amines Amides Reactions of Amides 1 Amines Organic compounds of nitrogen N Classified as primary, secondary, tertiary CH3 CH3

CH3NH2 CH3NH CH3N CH3 1 2 3 2 Naming Amines IUPAC aminoalkane CH3CH2NH2

aminoethane (ethylamine) Common alkylamine CH3NH CH3 N-methylaminomethane (dimethylamine) NH2 NH CH3 NH2 |

CH3CHCH3 2-aminopropane (isopropylamine) Aniline N-methylaniline 3 Learning Check AM1 Give the common name and classify and give the IUPAC name: A. CH3NHCH2CH3 CH3

| B. CH3CH2NCH3 4 Solution AM1 A. CH3NHCH2CH3 ethylmethylamine, 2, N-methylaminoethane CH3 | B. CH3CH2NCH3 ethyldimethylamine, 3, N,N-dimethylaminoethane 5

Reactions of Amines Act as weak bases in water CH3NH2 + H2O CH3NH3+ + OH methylammonium hydroxide Neutralization with acid gives ammonium salt CH3NH2 + HCl CH3NH3+ Cl methylammonium chloride 6

Alkaloids Physiologically active nitrogen-containing compounds Obtained from plants Used as anesthetics, antidepressants, and stimulants Many are addictive 7 Nicotine CH3 N

Nicotine, leaves of tobacco plant 8 Caffeine O CH3 O CH3 N N N

N CH3 Caffeine, coffee beans and tea 9 Procaine CH3CH2 O N

CH2CH2 O C NH2 CH3CH2 Procaine (novocaine), painkiller 10 Leaning Check AM2 Write a structural formula for A. 2-aminopentane

B. 1,3-diaminocyclohexane 11 Solution AM2 A. B. 1-aminopentane CH3CH2CH2CH2CH2-NH2

1,3-diaminocyclohexane NH 2 NH2 12 Amides Derivatives of carboxylic acids where an amino (-NH2) group replaces the OH group. O O

CH3 COH CH3 CNH2 carboxylic acid amide acetic acid acetamide 13

Naming Amides Alkanamide O HCNH2 from acid name methanamide (IUPAC) formamide (common) O CH3CH2CNH2

propanamide (IUPAC) propionamide(common) 14 Naming Amides with N-Groups O CH3CNHCH3 N-methylethanamide (IUPAC) N-methylacetamide (common) O

CH3CH2CN(CH3)2 N,N-dimethylpropanamide N,N-dimethylpropionamide 15 Aromatic Amides O O C NH2 C NHCH3

Benzamide N -methylbenzamide 16 Learning Check AM3 Name the following amides: O A. CH3CH2CH2CNH2 O

B. CH3CN(CH2CH3)2 17 Solution AM3 O A. CH3CH2CH2CNH2 butanamide; butryamide (common) O

B. CH3CN(CH2CH3)2 N,N-diethylethanamide; N,N-diethylacetamide 18 Learning Check AM4 Draw the structures of A. Pentanamide B. N-methylbutanamide 19

Solution AM4 A. Pentanamide O CH3CH2CH2CH2CNH2 B. N-methylbutanamide O CH3CH2CH2CNHCH3 20 Reactions of Amides

Amides undergo acid hydrolysis base hydrolysis carboxylic acid ammonium salt salt of carboxylic acid and an amine or ammonia 21 Reactions of Amides

acid hydrolysis O O HCl + H2O CH3COH + NH4+Cl CH3CNH2 NaOH

O CH3CO Na+ + NH3 base hydrolysis 22 Learning Check AM5 Write the products of the hydrolysis of N- ethylpropanamide with NaOH. 23

Solution AM5 Hydrolysis of N-ethylpropanamide with NaOH gives the following products. O CH3CH2CO Na+ + CH3CH2NH2 24

Recently Viewed Presentations

  • Program Planning: Models and Theories Why Theories and

    Program Planning: Models and Theories Why Theories and

    3. Perceptions, motivations, skills, and the social environment are key influences on behavior. Individual Level Interpersonal Level Community Level Group Work Chose a theoretical model or constructs that seem to be the best fir for your selected community issue and...
  • EXPRESS

    EXPRESS

    Saves you time and effort. No more mailing or faxing enrollment or change forms Around-the-clock access with real time updating Displays easy-to-use menu options to make your insurance updates quickly Obtains additional enrollment information when required for eligibility review How...
  • Peacock   By: Divena Gupta   Animal Facts  Description  Peacocks

    Peacock By: Divena Gupta Animal Facts Description Peacocks

    Peacocks live in groups called musters, prides, or ostentations there are 8-10 peacocks in each group, peacocks live to about 20 years, male peacocks have a blue body, long tails, and green and brown feathers, their body is 3-4 feet...
  • Montana General Supervision Enhancement Grant

    Montana General Supervision Enhancement Grant

    Montana Office of Public Instruction and Measured Progress. (2007, May). Determining the Feasibility of an Alternate Assessment Based on Modified Achievement Standards: A Planning Project and Pilot Test [Final Report for Montana's General Supervision Enhancement Grant CFDA 84.373X - Priority...
  • Pamela Haag's The Gunning of America: Creating a New Past

    Pamela Haag's The Gunning of America: Creating a New Past

    Pamela Haag's The Gunning of America: Creating a New Past. How Revisionist History Endangers the Second Amendment. Today I am speaking about a book that came out in 2015, and is likely going to influence future court decisions about the...
  • Practicing Bioinformatics A Tutorial for DS2005, 8 Oct 2005

    Practicing Bioinformatics A Tutorial for DS2005, 8 Oct 2005

    A Tutorial for DS2005, 8 Oct 2005 Wing-Kin Sung ... we can solve the problem in O(n2k+1 log n) time We devise a heuristic algorithm to solve it in O(n2(log n + k)) time Solution 4 Given two genomes S...
  • Diapositive 1 - 16.ticfga.ca

    Diapositive 1 - 16.ticfga.ca

    Classe dans les locaux du CJLRS et soutien individuel adapté CFP CÉA Le Moyne-D'Iberville CÉA Antoine-Brossard Comité local de Longueuil 6 projets Parent scolaire Depuis janvier 2005 CFP PARTENAIRES CSSS Pierre-Boucher CJE Longueuil Sécurité du revenu, direction régionale RESPONSABLE CÉA...
  • Join the Cloud! Robert Nordmark and Brian Burkhart

    Join the Cloud! Robert Nordmark and Brian Burkhart

    WebMail. Calendar. Address Book. 438 domains with 140,000 accounts. ... Can be used to interconnect two different types of media: For example, Ethernet to T1. ... Emulates the basic functions of a layer 2 switch: Unknown unicast flooding. Mac learning.