Histocompatibility Committee - UNOS

Histocompatibility Committee - UNOS

Histocompatibility Committee Spring 2017 1 Policy Implementation Dates Adding DQA1 Equivalency Table (2016) Identifies relationship between parent unacceptable antigens and corresponding allelic subtypes Implementation: second quarter 2017 Annual Update to Equivalency Tables (2015)

Adds alleles to HLA antigen dropdown options in UNet Changes HLA-DPB, HLA-DQA, and HLA-DQB references in policy to HLA-DPB1, HLA-DQA1, and HLA-DQB1 Adds dropdown values to DR51, DR52, DR53 Implementation: second quarter 2017 2 Committee Projects Public Comment Guidance Document

Clarifies OPTN bylaws and policies regarding histocompatibility testing Intended to be used by histocompatibility labs Distributed Projected for public comment: January 2017 to go to the Board June 2017 3 Committee Projects In Development

Addressing HLA Typing Errors in DonorNet UNOS sent letters to 14 labs to prevent future errors Considering programming options Review of HLA Equivalency Tables (2016) Creating a DPB1 resource Subcommittee Continuing reviewed epitopes

to work on developing tool by researching data sources 4 Questions? Robert Bray, Ph.D., D(ABHI), HCLD/CC(ABB) Committee Chair [email protected] Alison Wilhelm Committee Liaison [email protected] 5

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