NantHealth Management Meeting - Syracuse University

NantHealth Management Meeting - Syracuse University

PAF 101 Module 2, Lecture 5 No one can make you feel inferior without your consent. -Eleanor Roosevelt Class Agenda Announcements Help on 2.6 Bob Watson Competition Points Winners Losers As of 02/13/2017 Group # Total 17 13 14

10 10 8 16 8 4 6 2 6 5 6 8 6 13 6 18

6 6 4 15 4 3 3 7 3 9 3 1 2 11 2 12

2 Exercise 2.6 When stating your societal problem, make sure to use: Too little Too much Too low Too high Robert E. Watson, SU 1979 Policy Studies and Library Science President and Chief Growth Officer, NantHealth NASDAQ: NH Confidential Copyright Do not distribute Disclosure Statements This presentation has been prepared by NantHealth, Inc. (the Company) for informational purposes only and not for any other purpose. Nothing contained in this presentation is, or should be construed as, a recommendation, promise or representation by the presenter or the Company or any director, employee, agent, or adviser of the Company. This presentation does not purport to be all-inclusive or to contain all of the information you may desire. Information provided in this presentation speaks only as of the date hereof. The Company assumes no obligation to update any information or statement after the date of this presentation as a result of new information, subsequent events or any other circumstances. These materials and related materials and discussions may contain forward-looking statements that are based on the Companys current expectations, and projections and forecasts about future events and trends that the Company believes may affect its business, financial condition, operating results and growth prospects. Forward-looking statements are subject to substantial risks, uncertainties and other factors, including but not limited to (1) the structural change in the market for healthcare in the United States, including uncertainty in the healthcare regulatory framework and regulatory developments in the United States and foreign countries; (2) the evolving treatment paradigm for cancer, including physicians use of molecular information and targeted oncology therapeutics and the market size for molecular information products; (3) physicians need for precision medicine products and any perceived advantage of our solutions over those of our competitors, including the ability of our comprehensive platform to help physicians treat their patients cancers; (4) our ability to generate revenue from sales of products enabled by

our molecular and biometric information platforms to physicians in clinical settings; (5) our ability to increase the commercial success of our sequencing and molecular analysis solution; (6) our plans or ability to obtain reimbursement for our sequencing and molecular analysis solution, including expectations as to our ability or the amount of time it will take to achieve successful reimbursement from third-party payors, such as commercial insurance companies and health maintenance organizations, and government insurance programs, such as Medicare and Medicaid; (7) our ability to effectively manage our growth, including the rate and degree of market acceptance of our solutions; and (8) our ability to offer new and innovative products and services, attract new partners and clients, estimate the size of our target market, and maintain and enhance our reputation and brand recognition. The Company undertakes no obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by applicable law. No representation or warranty, express or implied, is given as to the completeness or accuracy of the information or opinions contained in this document and neither the Company nor any of its directors, members, officers, employees, agents or advisers accepts any liability for any direct, indirect or consequential loss or damage arising from reliance on such information or opinions. Past performance should not be taken as an indication or guarantee of future performance, and no representation or warranty, express or implied, is made regarding future performance. We own or have rights to trademarks and service marks that we use in connection with the operation of our business. NantHealth, Inc. and our logo as well as other protected brands. Solely for convenience, our trademarks and service marks referred to in this presentation are listed without the (sm) and (TM) symbols, but we will assert, to the fullest extent under applicable law, our rights or the rights of the applicable licensors to these trademarks, service marks and trade names. Additionally, we do not intend for our use or display of other companies trade names, trademarks, or service marks to imply a relationship with, or endorsement or sponsorship of us by, these other companies. We have indicated with (TM) symbols where these third party trademarks are referred to in this presentation. This presentation includes certain financial measures not based on accounting principles generally accepted in the United States, or non-GAAP measures. These non-GAAP measures are in addition to, not a substitute for or superior to, measures of financial performance prepared in accordance with GAAP. Confidential Copyright Do not distribute 6 How did we get here? SU 1979 Policy Studies and Library Science

UPenn, Wharton School of Business, 1981 1981-1983, Smith Barney, investment banking, healthcare 1983-1986, CFO, co-founder of AlternaCare Corp network of outpatient surgical centers, sold for $250MM+ 1988-1998, the decade of self realization 1999-2001, Cerner Corp (Nasdaq: CERN), Group CEO 2001-2015, CEO 3X, all turn arounds of troubled companies 2015-today, changing cancer care globally Confidential Copyright Do not distribute 7 Career Success. What matters? Showing up is critical Tom Brokaw, SU Graduation, 79 Skills matter Bill Coplin, everyday of his life (Thanks, Bill) Case in point: Library Science Huh?, Finance ok, maybe that skill makes sense, Investment Banking is there a skill here? Out work the other person See line one above Confidential Copyright Do not distribute

8 Multi-Billion Dollar, Rapidly Growing Market Opportunity Transition to Patient Centric, Value-Based Care $765bn of waste in the US Increased prevalence of valuebased models such as ACOs Lack of coordination / interoperability amongst silos of care $250bn precision medicine market Evolution toward comprehensive genomic and proteomic analysis Increased connectivity of biometric devices Overwhelming amounts of data and facts to arrive at a patient decision Confidential Copyright Do not distribute 9 Vision Toward Integrated Learning System for Healthcare 2 Precision Medicine

Define Rx Before Treatment Begins Integrate Complex Big-Data in RealTime 3 BioPharma At the Measure Diagnose Molecular Everything Level Genome, Proteome, Immunome, Metabolome 5 10 Precision Medicine Evidence-Based Guidelines DELIVERY DOMAIN

Global Scale BioPharma Clinical Trials Clinical Validity 7 Real-Time Connectivity Computer Algorithms that Improve with Experience 9 N=1 Precision Cancer Care The Era of Clinical Proteomics Neoepitope Therapy Engage: Patient, Provider, and Payor Allow Innovation Combination Trials for Adaptive + Rapid Approval Engage: Pharma

Right Place Right Time Right Caregiver Decision Support Care Coordination Clinical Pathways 12 8 Real-Time Learning Systems Mission Control Clinical Learning Outcomes Measurement Care Coordination & Outcomes Measurement 6 Engage: Patient &

Patient Informed Patient Advocate & Caregiver Patient Engagement At the Point of Care Connecting Academic Centers, Community Oncologists Machine Learning BioPharma Vaccine-Based Immuno-Oncology GPS-Driven Just in Treatment Personalized Time Novel Agents + Approved Drugs Combination Therapy & Drug Access KNOWLEDGE DOMAIN Right Diagnosis Right Decision

Right Rx 1 4 PAYOR DOMAIN Better Outcomes & Lower Cost 11 Payment For Value Support Payment for Evidence Based Care Self Payors & Major Insurers SYSTEMS INFRASTRUCTURE Real-Time Bioinformatics Device HIPAA Cloud NantHealth - Confidential, Do Connectivity Not Distribute Global Service

Oriented Architecture Confidential Copyright Do not distribute 10 My View: The healthcare system will change. How do you guys suggest we change it? What are your health policy ideas? Confidential Copyright Do not distribute 11 Thank You. 12 For next class Email prospective community service form to your TA by 2/17 or LOSE 5 POINTS Get started on Chapter 3 Exercises

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