Introduction Michael T. Parra MD Medical Director, PAS
Introduction Michael T. Parra MD Medical Director, PAS PROBLEM National Concern 60 Million Americans suffer from allergies 40% of children 30% of adults Allergies increased 50% since 1997
90% of asthma is triggered by allergies Testing is traumatic and treatment is time consuming RESULT Mask Symptoms Approximately 95% of patients go untreated! Still suffer dreaded trips to the ER Asthma attacks during sporting events, etc. Americans spent $17.5 Billion in 2010* ($18B in 2015)
antihistamines, decongestants, inhalers, steroids pills, eye drops, nasal sprays * Schaffer F. National Impact of Allergies. Academy of Allergy and Asthma in Primary Care. http://www.aaapc.us/wp-content/uploads/2013/01/National-Impact-of-Allergies.pdf (Retrieved April 8 2015) PROBLEM Why? (Standard Testing) Scratch Tests Painful 40-50 skin pricks Limited - only 40-50 allergens Time consuming 20-25 minutes 30% false positive results Subjective Observation alone Non-measurable as a repeatable PROBLEM Why? (Standard Testing) Intradermal Shots
Potential risks insert food & other allergens Subjective Observation only Non-measurable PROBLEM Why? (Standard Testing) Food Challenge Potential risks insert concentrated amount of food Tragic Result Alastair Watson Childrens Hospital of AL 07/30/17 PROBLEM Why? (Standard Treatment) Weekly shots (SCIT)
Time consuming Children are afraid of shots Titrate up 6-9 months to reach the maintenance level Do not feel better for at
(missed school & work) PROBLEM Why? (Standard Treatment) Sublingual drops (SLIT) Hold under tongue for two minutes forget to do Unpleasant taste Compliance 60% NO NEW DEVELOPMENTS IN ALLERGY TESTING AND TREATMENT PROTOCOLS IN USA
FOR 20 YEARS UNTIL NOW! SOLUTION NEW IN-OFFICE TEST & TREATMENT PROGRAM Now you can test and treat your allergy patients in your office! No longer need to refer over 95% of allergy patients to allergists As simple as 123 STEP ONE NEW TEST
Finger-prick blood test 120 allergens (compared to 40-50 with scratch tests) Unique Next-Generation Microarray Chip Assay Most advanced FDA cleared technology Simply drop 4 drops on specialized paper Airborne, environment & food 50 Allergen non-inhalant panel Foods, insects, latex, penicillin
70 Allergen environmental inhalant panel Animals, fungi, grass, insects, molds, trees, weeds FINGER-PRICK BLOOD TEST Sensitivity and Specificity Results Allergy tests correctly scored 20 positive and negative serum specimens for a total of 1,160 analytes for 100% sensitivity and 100% specificity for the inhalant allergens. Allergy tests correctly scored 20 positive and negative serum
specimens for a total of 660 analytes FINGER-PRICK BLOOD TEST Studies Asthma & Food Study of 215 children (1-14yrs) using ImmunoCAP Rapid testing demonstrated effective (88.4-97.6%) correct identification of allergic sensitization in children with recurrent asthma. Prospective food allergy study of this technology demonstrating the importance of quantitative IgE measurements in 100 children, referred for food allergy evaluation tested for IgE to egg, milk, peanut, soy, wheat, and fish after dx of food allergy established on hx and food challenge. Results showed greater than 95% of
food allergies were correctly identified, and could predict clinical (positive foodrapid challenges) with greater Diaz-Vazquez C, etreactivity al. Accuracy of ImmunoCAP(R) in the diagnosis of allergic sensitization in children between 1 and 14 years with than 95%thecertainty. recurrent wheezing: IReNE study. Pediatric Allergy Immunol 2009;20:601-9.
Sampson HA. Utility of food specific IgE concentrations in predicting symptomatic food allergy. J Allergy Clin Immunol 2001;107:891-6. STEP ONE NEW TEST Finger-Prick Blood Test Safe, Fast & Easy Four Drops of Blood Measurable results Eliminates need for Food Challenge Safe!
Comprehensive 120 Allergens vs 40-50 with Scratch Test Non-Inhalant and Environmental Allergens Acremonium, Alder, Alfalfa Pollen, Alternaria, Aspergillus, Auareobasidum, Australian Pine, Bahia grass, Bald cypress, Bayberry (wax myrtle), Bermuda grass, Birch White, Box Elder, California Live Oak, Candida Albicans, Cat Hair, Cattle Hair, Cedar Red, Cedar Mountain, Cladosporium, Cocklebur, Cockroach Mix, Cottonwood, Curvularia, Dog Hair, Drechslera, Elm American, Elm Chinese, English planain, Epicoccum, Fusarium, Horse Hair, Johnson Grass, June Grass, Juniper, Kochia, Lamb's Quarters, Maple Pollen, Mite Farinae, Mite Pteronyssinus,
STEP TWO PRESCRIBE Write prescription for customized serum Compounding pharmacy Mixes unique allergen serum, based on finger stick non-food allergen results STEP THREE TOOTHPASTE Oral Mucosal Immunotherapy (OMIT)
Serum is mixed in OMIT base to create prescribed toothpaste Patient returns quarterly for checkup and receive next 90-day supply STEP THREE NEW TOOTHPASTE Safe - Natural
Begin at maintenance level (vs. Patients feel better faster Increase compliance More effective than SCIT (shots) or SLIT (sublingual drops) titrate up 6-9 months) BENEFITS To Practice Solve a national concern
Provide testing & treatment in office Measurable Results Natural, safe, effective regimen specifically designed for non-food allergies New revenue: Quarterly office visits Admin fee with Treatment
BENEFITS To Patient Not Scary/Quick - Prick finger Effective Natural therapy Safe Drop blood on card for testing Simple Brush teeth for 2 min Tastes good
Berry or Mint flavor BENEFITS To Parents/Patients Save Time Save Money
No weekly trips to allergist No missed work or school Gas, parking fees, time No copays ($20-$50 per visit) Easy & sustainable treatment Brush teeth daily for 2 minutes SUMMARY Unique Microarray Chip Assay (Test) Prescribe
Toothpaste Drop 4 Drops of blood on card (safe/quick) 120 Allergens (vs 40-50 with scratch testing) Measurable results (from test to test) Unique serum per patient Most effective delivery system (start at
Saves money ($120 for shots vs. $105) maintenance level vs. titrating up 6-9 months like with shots) RESULT Replace or enhance out-dated: Replace weekly shots (time consuming) Replace sublingual drops (unpleasant taste) Treat 95% of patients in office! (currently
Scratch test Intradermal test Food Challenge untreated) Feel better sooner Compliant completion of regimen LEARN MORE
Is this safe? Does it work? For more information, go to: www.PediatricAllergySolutions.com
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