Role and Importance of Applied Biochemistry in Animal Nutrition

Role and Importance of Applied Biochemistry in Animal Nutrition

Metabolism of Nutrients in Stomach and Intestine Anusorn Cherdthong, PhD 137748 Applied Biochemistry in Nutritional Science Email: [email protected] E-learning: http://ags.kku.ac.th/eLearning/137748 Introduction

Metabolism: Catabolism: large small molecule and receiving ATP Anabolism: small large molecule and spend ATP, NADPH Metabolism in stomach

Carbohydrate: overview Mouth: -amylase Teeth Esophagus Stomach: no amylase Small/large intestine: enzymes Rectal: excretion

Metabolism in stomach Wanapat et al. (2013) Metabolism in stomach Carbohydrate: Rumen metabolism

poly mono saccharide: extracellular microbial enzyme: Cellulosecellobiose Hemicellulosecellobiose Pectinmethanol and pectic acid Mono saccharidepyruvate Pyruvate---VFA, CH4

C2, C3 and C4 Metabolism in stomach Carbohydrate: Rumen metabolism McDonald et al. (2011)

Metabolism in stomach VFV synthesis in rumen McDonald et al. (2011) Metabolism in stomach Protein: overview in stomach

Gastrin hormone HCl excretion: low pH (2.0) Pepsinogen excretion: proenzyme for peptide degrade Metabolism in stomach Protein: Rumen

Proteiolytic microorganism Bacteria Protozoa Fungi McDonald et al. (2011)

Metabolism in stomach Lipid: overview in stomach No digest in non ruminant stomach Ruminant act by rumen microbes by: Hydrolysis Hydrogenation

Isomerization Metabolism in intestine Carbohydrate: Require enzyme for pancreases: -amylase -glucosidase

Maltase -dextrinase Metabolism in intestine Protein metabolism in small intestine: Modified from Cunningham (1992)

Metabolism in intestine Protein metabolism in small intestine: Modified from Cunningham (1992) Metabolism in intestine

Lipid metabolism in small intestine: Triacyl glycerol Required bile salt as emulsifier Excreate cholecystokinin and secretin Formulation of mixed micelle for transfer and absorption

Bile recycle when reaction finished Required pancreatic lipase Metabolism in intestine Lipid: Absorption Chylomicron: lipoprotein Via lymph system--blood---tissue

Metabolism in liver, storage Nelson and Cox (2000) Metabolism in large intestine: A few metabolism in this part

Digest some cellulose by-pass Work by bacteria Re-absorption of nutrients Essential for equine: fiber digestion Conclusion 1

Metabolism of nutrient in stomach 2 3 Metabolism of nutrient in intestine

Utilization of nutrient in different animal al species Thank you!

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