Effectiveness of premedication agents administered prior to nitrous : oxide/oxygen. (10 ) - premedication : - Research question - Study population: ? - Study design: ? - Study context - Result (Informative): Oral premedication with midazolam but not hydroxyzine hydrochloride increases sedation success rate in children undergoing dental treatments A Good Title
-Complete -Good description of the content -Brief -Concise Background/Introduction : , - , -
- 5 x R2R - 5 x ( ) ...?........ Routine Practice?.
() ........ MO( 30 )/ ? Morphine guideline Including a clear statement of
the main aim(s) of the study and the major hypothesis tested or research question posed. Avoid statement such as we aimed to evaluate the effectiveness of the x /Methods 2 : - sample size, numbers of patients in different groups, doses of medications, and duration of the study. -
/Methods 1. 2. 3. ( ) 4. () 5. 6. Intervention treatment dose ? 7. 8. Setting: Include the level of care e.g. primary, secondary; number of
participating centres. Be general rather than give the name of the specific centre, bu t give the geographical location if this is important. Include the dates of the study period Checklist 1. 2. 3. 4. 5. 6. 7. 8. 9. ( )
Response rates differed significantly between diabetic and nondiabetic Drop out rate primary outcome ( P values) secondary outcomes ( P values) standard deviation, 95% CI, response and remission rates, effect sizes, Conclusions
2-3 3 : -The primary take-home message -The additional findings of importance -The perspective: : theoretical or practical implications of the findings, or the importance of their findings for the
field. lab, software :
Chi-square = 7.49, df = 1, p < 0.001 paper RCT, Observational Diagnostic Studies Background: Explaining the clinical (or other) importance of the study question.
Objective(s): Including a clear statement of the main aim(s) of the study and the major hypothesis tested or research question posed. Avoid statements such as We aimed to evaluate the effectiveness of X. Design: For example, randomised controlled study, case control study, crossover study, observational study, survey, diagnostic test etc. Setting: Include the level of care e.g. primary, secondary; number of participating centres. Be general rather than give the name of the specific centre, but give the geographical location if this is important. Inc lude the dates of the study period. Patients, other participants (for instance, volunteers) (delete what does not apply): Numbers entering and completing the study, sex, and ethnic group of patients if appropriate. Give clear definitions of how selected, e ntry and exclusion criteria. For animal studies, this information should be included in the Design or Setting section. RCT, Observational Diagnostic Intervention(s): What, how, when and for how long. This Studies heading can
be deleted if there were no interventions but should normally be included for randomised controlled trials, cross over trials, and before and after st udies. Main outcome measures: What was the primary endpoint? What outcome measures were planned in protocol, which were finally measured (if different, explain why)? Results: Main results with (for quantitative studies) 95% confidence intervals and, where appropriate, the exact level of statistical significance. Conclusions: Primary conclusions and their implications, suggest areas for further research if appropriate. Guidance for Authors; European Journal of Anaesthesiology
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Systolic Click. Very sharp, high frequency click of Mitral valve prolapse, in early MVD. Snapping of the chordae tendinae as they go taught. PMI left apex. Mid-Systolic (audio) (audio) May be accompanied by a systolic murmur. Early, late, or holosystolic....
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