Sliding Filament Model of Muscle Contraction

Sliding Filament Model of Muscle Contraction

Fig. 10-3. Myofibrils are surrounded by calciumcontaining sarcoplasmic reticulum. Fig. 10-7. Review of thin and

thick filament structure Fig. 10-9. Overview of the process Fig. 10-9. Overview of the process The muscle fiber is

stimulated. Fig. 10-9. Overview of the process The muscle fiber is stimulated. Ca2+ ions are released.

Fig. 10-11. Endon view of thick & thin filaments, showing the effect of calcium ions after release from the S.R. Fig. 10-9. Overview of

the process The muscle fiber is stimulated. Ca2+ ions are released. Fig. 10-9. Overview of the process The muscle fiber is

stimulated. Ca2+ ions are released. Thin filaments move to middle of sarcomere. Fig. 10-12 Calcium attaches to

troponin/ tropomyosin; they roll away, exposing the active site on actin. Fig. 10-12 Myosin cross-bridges attach to active site on actin.

After attachment, the cross-bridges pivot, pulling the thin filaments. Fig. 10-12 A fresh ATP replaces the

ADP+Pi, allowing myosin and actin to detach. Energy from the splitting of the fresh ATP allows repositioning of the myosin head.

Fig. 10-12 This leads back to Step 1, which continues the cycle as long as calcium ions are attached to

troponin/tropomyosin. Fig. 10-9. Overview of the process The muscle fiber is stimulated. Ca2+ ions are released. Thin filaments move to

middle of sarcomere. Fig. 10-9. Overview of the process The muscle fiber is stimulated. Ca2+ ions are released. Thin filaments move to

middle of sarcomere. Muscle fiber contracts. Fig. 10-9. Overview of the process The muscle fiber is stimulated. Ca2+ ions are released.

Thin filaments move to middle of sarcomere. Muscle fiber contracts. Muscle tension increases.

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